Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner. Rauf F, Festa F, Park JG, Magee M, Eaton S, Rinaldi C, Betanzos CM, Gonzalez-Malerva L, LaBaer J. Oncogene. 2018 Feb 5. doi: 10.1038/s41388-017-0079-x. [Epub ahead of print]
Autoantibody biomarkers for the detection of serous ovarian cancer. Katchman BA, Chowell D, Wallstrom G, Vitonis AF, LaBaer J, Cramer DW, Anderson KS. Gynecol Oncol. 2017 Jul;146(1):129-136. doi: 10.1016/j.ygyno.2017.04.005. Epub 2017 Apr 18
Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B’, as an Autoantibody Marker in Crohn’s Disease using an Immunoproteomics Approach. Wang H, Demirkan G, Bian X, Wallstrom G, Barker K, Karthikeyan K, Tang Y, Pasha SF, Leighton JA, Qiu J, LaBaer J. J Crohns Colitis. 2017 Jul 1;11(7):848-856. doi: 10.1093/ecco-jcc/jjx019.
Identification of Antibody Targets for Tuberculosis Serology using High-Density Nucleic Acid Programmable Protein Arrays. Song L, Wallstrom G, Yu X, Hopper M, Van Duine J, Steel J, Park J, Wiktor P, Kahn P, Brunner A, Wilson D, Jenny-Avital ER, Qiu J, Labaer J, Magee DM, Achkar JM. Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S277-S289. doi: 10.1074/mcp.M116.065953. Epub 2017 Feb 21.
Tracking the Antibody Immunome in Type 1 Diabetes Using Protein Arrays. Bian X, Wasserfall C, Wallstrom G, Wang J, Wang H, Barker K, Schatz D, Atkinson M, Qiu J, LaBaer J. J Proteome Res. 2017 Jan 6;16(1):195-203. doi: 10.1021/acs.jproteome.6b00354. Epub 2016 Oct 17.
Mapping transcription factor interactome networks using HaloTag protein arrays. Yazaki J, Galli M, Kim AY, Nito K, Aleman F, Chang KN, Carvunis AR, Quan R, Nguyen H, Song L, Alvarez JM, Huang SS, Chen H, Ramachandran N, Altmann S, Gutiérrez RA, Hill DE, Schroeder JI, Chory J, LaBaer J, Vidal M, Braun P, Ecker JR. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4238-47. doi: 10.1073/pnas.1603229113. Epub 2016 Jun 29.
Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers. Katchman BA, Barderas R, Alam R, Chowell D, Field MS, Esserman LJ, Wallstrom G, LaBaer J, Cramer DW, Hollingsworth MA, Anderson KS. Proteomics Clin Appl. 2016 Jul;10(7):720-31. doi: 10.1002/prca.201500096. Epub 2016 May 17.
Comparative Study of Autoantibody Responses between Lung Adenocarcinoma and Benign Pulmonary Nodules. Wang J, Shivakumar S, Barker K, Tang Y, Wallstrom G, Park JG, Tsay JC, Pass HI, Rom WN, LaBaer J, Qiu J. J Thorac Oncol. 2016 Mar;11(3):334-45. doi: 10.1016/j.jtho.2015.11.011. Epub 2016 Feb 16.
Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays. Bian X, Wallstrom G, Davis A, Wang J, Park J, Throop A, Steel J, Yu X, Wasserfall C, Schatz D, Atkinson M, Qiu J, LaBaer J. Diabetes. 2016 Jan;65(1):285-96. doi: 10.2337/db15-0179. Epub 2015 Oct 8.
Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays. Olia AS, Barker K, McCullough CE, Tang HY, Speicher DW, Qiu J, LaBaer J, Marmorstein R. ACS Chem Biol. 2015 Sep 18;10(9):2034-47. doi: 10.1021/acschembio.5b00342. Epub 2015 Jun 23.
Plasma Autoantibodies Associated with Basal-like Breast Cancers. Wang J, Figueroa JD, Wallstrom G, Barker K, Park JG, Demirkan G, Lissowska J, Anderson KS, Qiu J, LaBaer J. Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1332-40. doi: 10.1158/1055-9965.EPI-15-0047. Epub 2015 Jun 12.
Host-pathogen interaction profiling using self-assembling human protein arrays. Yu X, Decker KB, Barker K, Neunuebel MR, Saul J, Graves M, Westcott N, Hang H, LaBaer J, Qiu J, Machner MP. J Proteome Res. 2015 Apr 3;14(4):1920-36. doi: 10.1021/pr5013015. Epub 2015 Mar 18.
Autoantibody signature for the serologic detection of ovarian cancer. Anderson KS, Cramer DW, Sibani S, Wallstrom G, Wong J, Park J, Qiu J, Vitonis A, LaBaer J. J Proteome Res. 2015 Jan 2;14(1):578-86. doi: 10.1021/pr500908n. Epub 2014 Nov 17.
Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays. Yu X, Woolery AR, Luong P, Hao YH, Grammel M, Westcott N, Park J, Wang J, Bian X, Demirkan G, Hang HC, Orth K, LaBaer J. Mol Cell Proteomics. 2014 Nov;13(11):3164-76. doi: 10.1074/mcp.M114.041103. Epub 2014 Jul 29.
Serological autoantibody profiling of type 1 diabetes by protein arrays. Miersch S, Bian X, Wallstrom G, Sibani S, Logvinenko T, Wasserfall CH, Schatz D, Atkinson M, Qiu J, LaBaer J. J Proteomics. 2013 Dec 6;94:486-96. doi: 10.1016/j.jprot.2013.10.018. Epub 2013 Oct 20.
Self-assembled protein arrays from an Ornithodoros moubata salivary gland expression library. Manzano-Román R, Díaz-Martín V, González-González M, Matarraz S, Álvarez-Prado AF, LaBaer J, Orfao A, Pérez-Sánchez R, Fuentes M. J Proteome Res. 2012 Dec 7;11(12):5972-82. doi: 10.1021/pr300696h. Epub 2012 Nov 20.
Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays. Gibson DS, Qiu J, Mendoza EA, Barker K, Rooney ME, LaBaer J. Arthritis Res Ther. 2012 Apr 17;14(2):R77. doi: 10.1186/ar3800.
Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays. Wright C, Sibani S, Trudgian D, Fischer R, Kessler B, LaBaer J, Bowness P. Mol Cell Proteomics. 2012 Feb;11(2):M9.00384. doi: 10.1074/mcp.M9.00384.
Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. Anderson KS, Wong J, D’Souza G, Riemer AB, Lorch J, Haddad R, Pai SI, Longtine J, McClean M, LaBaer J, Kelsey KT, Posner M. Br J Cancer. 2011 Jun 7;104(12):1896-905. doi: 10.1038/bjc.2011.171.
Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer. Anderson KS, Sibani S, Wallstrom G, Qiu J, Mendoza EA, Raphael J, Hainsworth E, Montor WR, Wong J, Park JG, Lokko N, Logvinenko T, Ramachandran N, Godwin AK, Marks J, Engstrom P, Labaer J. J Proteome Res. 2011 Jan 7;10(1):85-96. doi: 10.1021/pr100686b. Epub 2010 Nov 23.
Systematic analysis of the IgG antibody immune response against varicella zoster virus (VZV) using a self-assembled protein microarray. Ceroni A, Sibani S, Baiker A, Pothineni VR, Bailer SM, LaBaer J, Haas J, Campbell CJ. Mol Biosyst. 2010 Sep;6(9):1604-10. doi: 10.1039/c003798b. Epub 2010 Jun 1.
Use of a single-chain antibody library for ovarian cancer biomarker discovery. Ramirez AB, Loch CM, Zhang Y, Liu Y, Wang X, Wayner EA, Sargent JE, Sibani S, Hainsworth E, Mendoza EA, Eugene R, Labaer J, Urban ND, McIntosh MW, Lampe PD. Mol Cell Proteomics. 2010 Jul;9(7):1449-60. doi: 10.1074/mcp.M900496-MCP200. Epub 2010 May 13.
Genome-wide study of Pseudomonas aeruginosa outer membrane protein immunogenicity using self-assembling protein microarrays. Montor WR, Huang J, Hu Y, Hainsworth E, Lynch S, Kronish JW, Ordonez CL, Logvinenko T, Lory S, LaBaer J. Infect Immun. 2009 Nov;77(11):4877-86. doi: 10.1128/IAI.00698-09. Epub 2009 Sep 8.
Advances in cell-free protein array methods. Yu X, Petritis B, Duan H, Xu D, LaBaer J. Expert Rev Proteomics. 2018 Jan;15(1):1-11. doi: 10.1080/14789450.2018.1415146. Epub 2017 Dec 13.
Automatic Identification and Quantification of Extra-Well Fluorescence in Microarray Images. Rivera R, Wang J, Yu X, Demirkan G, Hopper M, Bian X, Tahsin T, Magee DM, Qiu J, LaBaer J, Wallstrom G. J Proteome Res. 2017 Nov 3;16(11):3969-3977. doi:10.1021/acs.jproteome.7b00267. Epub 2017 Oct 10.
Multiplexed Nucleic Acid Programmable Protein Arrays. Yu X, Song L, Petritis B, Bian X, Wang H, Viloria J, Park J, Bui H, Li H, Wang J, Liu L, Yang L, Duan H, McMurray DN, Achkar JM, Magee M, Qiu J, LaBaer J. Theranostics. 2017 Sep 20;7(16):4057-4070. doi: 10.7150/thno.20151. eCollection 2017.
Discovering Protein-Protein Interactions Using Nucleic Acid Programmable Protein Arrays. Tang Y, Qiu J, Machner M, LaBaer J. Curr Protoc Cell Biol. 2017 Mar 3;74:15.21.1-15.21.14. doi: 10.1002/cpcb.14.
A Contra Capture Protein Array Platform for Studying Post-translationally Modified (PTM) Auto-antigenomes. Karthikeyan K, Barker K, Tang Y, Kahn P, Wiktor P, Brunner A, Knabben V, Takulapalli B, Buckner J, Nepom G, LaBaer J, Qiu J. Mol Cell Proteomics. 2016 Jul;15(7):2324-37. doi: 10.1074/mcp.M115.057661. Epub 2016 May 2.
Advancing translational research with next-generation protein microarrays. Yu X, Petritis B, LaBaer J. Proteomics. 2016 Apr;16(8):1238-50. doi: 10.1002/pmic.201500374. Epub 2016 Mar 31. Review.
Antiviral antibody profiling by high-density protein arrays. Bian X, Wiktor P, Kahn P, Brunner A, Khela A, Karthikeyan K, Barker K, Yu X, Magee M, Wasserfall CH, Gibson D, Rooney ME, Qiu J, LaBaer J. Proteomics. 2015 Jun;15(12):2136-45. doi: 10.1002/pmic.201400612. Epub 2015 May 15.
High-throughput identification of proteins with AMPylation using self-assembled human protein (NAPPA) microarrays. Yu X, LaBaer J. Nat Protoc. 2015 May;10(5):756-67. doi: 10.1038/nprot.2015.044. Epub 2015 Apr 16.
NAPPA as a Real New Method for Protein Microarray Generation. Díez P, González-González M, Lourido L, Dégano RM, Ibarrola N, Casado-Vela J, LaBaer J, Fuentes M. Microarrays (Basel). 2015 Apr 24;4(2):214-27. doi: 10.3390/microarrays4020214. Review.
Microreactor array device. Wiktor P, Brunner A, Kahn P, Qiu J, Magee M, Bian X, Karthikeyan K, LaBaer J. Sci Rep. 2015 Mar 4;5:8736. doi: 10.1038/srep08736.
Exploration of panviral proteome: high-throughput cloning and functional implications in virus-host interactions. Yu X, Bian X, Throop A, Song L, Moral LD, Park J, Seiler C, Fiacco M, Steel J, Hunter P, Saul J, Wang J, Qiu J, Pipas JM, LaBaer J. Theranostics. 2014 Jun 6;4(8):808-22. doi: 10.7150/thno.8255. eCollection 2014.
Robust microarray production of freshly expressed proteins in a human milieu. Festa F, Rollins SM, Vattem K, Hathaway M, Lorenz P, Mendoza EA, Yu X, Qiu J, Kilmer G, Jensen P, Webb B, Ryan ET, LaBaer J. Proteomics Clin Appl. 2013 Jun;7(5-6):372-7. doi: 10.1002/prca.201200063. Epub 2013 May 17.
A versatile protein microarray platform enabling antibody profiling against denatured proteins. Wang J, Barker K, Steel J, Park J, Saul J, Festa F, Wallstrom G, Yu X, Bian X, Anderson KS, Figueroa JD, LaBaer J, Qiu J. Proteomics Clin Appl. 2013 Jun;7(5-6):378-83. doi: 10.1002/prca.201200062. Epub 2013 May 17.
Quantifying antibody binding on protein microarrays using microarray nonlinear calibration. Yu X, Wallstrom G, Magee DM, Qiu J, Mendoza DE, Wang J, Bian X, Graves M, LaBaer J. Biotechniques. 2013 May;54(5):257-64. doi: 10.2144/000114028.
High density diffusion-free nanowell arrays. Takulapalli BR, Qiu J, Magee DM, Kahn P, Brunner A, Barker K, Means S, Miersch S, Bian X, Mendoza A, Festa F, Syal K, Park JG, LaBaer J, Wiktor P. J Proteome Res. 2012 Aug 3;11(8):4382-91. doi: 10.1021/pr300467q. Epub 2012 Jul 13.
MALDI-TOF characterization of NAPPA-generated proteins. Spera R, Labaer J, Nicolini C. J Mass Spectrom. 2011 Sep;46(9):960-5. doi: 10.1002/jms.1976. No abstract available.
Nucleic Acid programmable protein arrays: versatile tools for array-based functional protein studies. Miersch S, LaBaer J. Curr Protoc Protein Sci. 2011 Apr;Chapter 27:Unit27.2. doi: 10.1002/0471140864.ps2702s64.
Nucleic acid programmable protein array a just-in-time multiplexed protein expression and purification platform. Qiu J, LaBaer J. Methods Enzymol. 2011;500:151-63. doi: 10.1016/B978-0-12-385118-5.00009-8.
Immunoprofiling using NAPPA protein microarrays. Sibani S, LaBaer J. Methods Mol Biol. 2011;723:149-61. doi: 10.1007/978-1-61779-043-0_10.
Rapid detection of antibodies in sera using multiplexed self-assembling bead arrays. Wong J, Sibani S, Lokko NN, LaBaer J, Anderson KS. J Immunol Methods. 2009 Oct 31;350(1-2):171-82. doi: 10.1016/j.jim.2009.08.013. Epub 2009 Sep 2.
Using the Nucleic Acid Programmable Protein Array (NAPPA) for Identifying Protein-Protein Interactions. Protocol 2: Detection of Query Proteins on NAPPA Slides. Link AJ, Labaer J. CSH Protoc. 2008 Dec 1;2008:pdb.prot5109. doi: 10.1101/pdb.prot5109.
Using the Nucleic Acid Programmable Protein Array (NAPPA) for Identifying Protein-Protein Interactions. Protocol 1: Coexpression of Query Protein on NAPPA Slides. Link AJ, Labaer J. CSH Protoc. 2008 Dec 1;2008:pdb.prot5108. doi: 10.1101/pdb.prot5108
Using the Nucleic Acid Programmable Protein Array (NAPPA) for Identifying Protein-Protein Interactions: General Guidelines. Link AJ, Labaer J. CSH Protoc. 2008 Dec 1;2008:pdb.ip62. doi: 10.1101/pdb.ip62.
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 7: Detecting DNA on NAPPA Slides. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5062. doi: 10.1101/pdb.prot5062.
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 6: Detecting Proteins on NAPPA Slides. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5061. doi: 10.1101/pdb.prot5061.
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 5: Expressing Proteins on NAPPA Slides. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5060. doi: 10.1101/pdb.prot5060.
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 4: DNA Biotinylation, Precipitation, and Arraying of Samples. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5059. doi: 10.1101/pdb.prot5059.
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 3: Isolating DNA Plasmids in a 96-Well Plate Format. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5058. doi: 10.1101/pdb.prot5058
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 2: Preparing Bacterial Cultures in a 96-Well Format. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5057. doi: 10.1101/pdb.prot5057.
Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 1: Coating Glass Slides with Amino Silane. Link AJ, Labaer J. CSH Protoc. 2008 Nov 1;2008:pdb.prot5056. doi: 10.1101/pdb.prot5056.
Tracking humoral responses using self-assembling protein microarrays. Ramachandran N, Anderson KS, Raphael JV, Hainsworth E, Sibani S, Montor WR, Pacek M, Wong J, Eljanne M, Sanda MG, Hu Y, Logvinenko T, Labaer J. Proteomics Clin Appl. 2008 Oct;2(10-11):1518-27. doi: 10.1002/prca.200800034. Epub 2008 Sep 10.
Applications of protein microarrays for biomarker discovery. Ramachandran N, Srivastava S, Labaer J. Proteomics Clin Appl. 2008 Oct;2(10-11):1444-59. doi: 10.1002/prca.200800032. Epub 2008 Sep 10.
Next-generation high-density self-assembling functional protein arrays. Ramachandran N, Raphael JV, Hainsworth E, Demirkan G, Fuentes MG, Rolfs A, Hu Y, LaBaer J. Nat Methods. 2008 Jun;5(6):535-8. doi: 10.1038/nmeth.1210. Epub 2008 May 11.
Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. Anderson KS, Ramachandran N, Wong J, Raphael JV, Hainsworth E, Demirkan G, Cramer D, Aronzon D, Hodi FS, Harris L, Logvinenko T, LaBaer J. J Proteome Res. 2008 Apr;7(4):1490-9. doi: 10.1021/pr700804c. Epub 2008 Feb 27.
On-chip protein synthesis for making microarrays. Ramachandran N, Hainsworth E, Demirkan G, LaBaer J. Methods Mol Biol. 2006;328:1-14.
Emerging tools for real-time label-free detection of interactions on functional protein microarrays. Ramachandran N, Larson DN, Stark PR, Hainsworth E, LaBaer J. FEBS J. 2005 Nov;272(21):5412-25. Review.
Protein microarrays as tools for functional proteomics. LaBaer J, Ramachandran N. Curr Opin Chem Biol. 2005 Feb;9(1):14-9. Review.
Self-assembling protein microarrays. Ramachandran N, Hainsworth E, Bhullar B, Eisenstein S, Rosen B, Lau AY, Walter JC, LaBaer J. Science. 2004 Jul 2;305(5680):86-90.